Daniel Barrister is a God fearing man whose wife is badly injured in an accident on the trail. Daniel puts his faith in the Lord as the one great healer to heal his wife, but her condition gradually worsens. When infection sets in, the Major uses his authority as Wagonmaster to over-ride Daniel Barrister's wishes. He sends Flint McCullough to the nearest town to find a doctor. When Flint gets there he finds the town quarantined because of a smallpox outbreak. (thetvdb.com)